DeRionne serves as President of Montgomery College, one of largest undergraduate institutions in the state of Maryland, which educates nearly 60,000 credit and noncredit students annually at its three campuses. She is passionate about seeking innovative ways to increase student access and success, such as a new partnership with Montgomery County Public Schools and the Universities of Shady Grove to create Achieving Collegiate Excellence and Success (ACES), a support program designed to help first generation and minority students seamlessly transition from high school to college completion by embedding college coaches from Montgomery College in the high schools. She has championed access to effective education, training, and counseling programs to the adult incarcerated population and to at-risk juveniles.