This month, six Americans, including three chemists and three biologists, were honored with one of the scientific community’s highest honors, the Nobel Prize. Sharing the 2013 Prize in Physiology or Medicine were James E. Rothman, Randy W. Schekman, and Thomas C. Südhof, while the Prize in Chemistry went to Martin Karplus, Michael Levitt, and Arieh Warshel. OSTP Director John P. Holdren called each of the winners to congratulate them.